Peptide Therapy
Targeted peptide protocols for growth hormone optimization, tissue repair, body composition, and recovery — working with your body's natural signaling systems to enhance performance and slow aging.
What Is Peptide Therapy?
Peptides are short chains of amino acids — typically 2 to 50 amino acids long — that act as signaling molecules in your body. They tell cells what to do: produce more growth hormone, repair damaged tissue, reduce inflammation, or modulate immune function. Your body naturally produces thousands of peptides, but production declines with age.
Peptide therapy uses synthetic versions of these natural compounds to restore or enhance specific biological processes. Unlike traditional medications that often override your body's systems, peptides work with your natural biology — stimulating your own cells to do what they're designed to do, just more effectively.
At Rewind Anti-Aging, we prescribe peptides for three primary goals:
- Growth hormone optimization — stimulating your pituitary gland to produce more HGH naturally (sermorelin, CJC-1295, ipamorelin, tesamorelin)
- Tissue repair and recovery — accelerating healing of injuries, gut repair, and reducing inflammation (BPC-157, TB-500)
- Body composition — reducing visceral fat, increasing lean muscle mass, and improving metabolic function
Peptides We Prescribe
Nine targeted peptides selected based on your goals, labs, and biology — not a one-size-fits-all approach.
Sermorelin
GH OptimizationGHRH receptor agonist that stimulates natural GH release, primarily during deep sleep
CJC-1295
GH OptimizationLong-acting GHRH analog for sustained growth hormone and IGF-1 elevation
Ipamorelin
GH OptimizationSelective ghrelin receptor agonist for clean GH boost with minimal side effects
Tesamorelin
Body CompositionFDA-approved GHRH analog with strongest data for visceral fat reduction
BPC-157
Tissue RepairBody Protection Compound for tissue repair, gut healing, and injury recovery
TB-500
Tissue RepairSystemic repair peptide for wound healing, inflammation reduction, and flexibility
MOTS-c
LongevityMitochondrial peptide for metabolic optimization and cellular energy
Melanotan II
Aesthetics & Sexual HealthAlpha-MSH analog for tanning and sexual function support
Thymullin
Immune SupportThymic peptide for immune system restoration and anti-aging
Growth Hormone Secretagogues: Optimizing HGH Naturally
Human growth hormone (HGH) is one of the most important hormones for maintaining youthful body composition, energy, recovery, sleep quality, and skin health. But HGH production peaks in your 20s and declines approximately 14% per decade after age 30. By 60, most people produce a fraction of the growth hormone they did at 25.
Growth hormone secretagogues (GHSs) don't inject synthetic growth hormone — they stimulate your own pituitary gland to produce and release more HGH naturally. This preserves your body's feedback mechanisms and produces a more physiological response than exogenous HGH.
Sermorelin
Sermorelin is a synthetic analog of growth hormone-releasing hormone (GHRH) — the natural peptide your hypothalamus uses to signal the pituitary gland. It contains the first 29 amino acids of GHRH, which is the biologically active portion.
How it works: Binds to GHRH receptors on the pituitary gland, stimulating the production and release of HGH in a pulsatile pattern that mimics your body's natural rhythm — primarily during deep sleep.
Key benefits:
- Improved sleep quality and depth (often the first noticeable benefit)
- Increased lean muscle mass and strength
- Reduced body fat, particularly visceral abdominal fat
- Enhanced skin elasticity and collagen production
- Improved bone density
- Better mood and cognitive function
Administration: Subcutaneous injection, typically administered nightly before bed to align with the body's natural growth hormone release cycle.
CJC-1295
CJC-1295 is a modified GHRH analog with a key advantage over sermorelin: a significantly longer half-life. While sermorelin is active for minutes, CJC-1295 (with Drug Affinity Complex/DAC) remains active for days, producing sustained elevation of growth hormone and IGF-1 levels.
How it works: Increases the production of GHRH, which in turn stimulates the pituitary gland to produce more HGH. The longer half-life means more consistent GH elevation between doses.
Key benefits:
- Increased muscle mass and improved bone density
- Reduced body fat with sustained GH elevation
- Enhanced recovery between workouts
- More stable, sustained growth hormone levels than sermorelin
Administration: Subcutaneous injection, typically 2-3 times per week.
Ipamorelin
Ipamorelin is a growth hormone-releasing peptide (GHRP) that works through a different receptor than sermorelin and CJC-1295. While those peptides work through GHRH receptors, ipamorelin binds to ghrelin receptors on the pituitary gland.
How it works: Ipamorelin is the most selective GHRP available — it stimulates growth hormone release without significantly affecting other hormones like cortisol, prolactin, or ACTH. This selectivity means fewer side effects and a cleaner hormonal response than older GHRPs.
Key benefits:
- Selective GH release without cortisol or prolactin spikes
- Fewer side effects than other GH-releasing peptides
- Clean hormonal response with minimal disruption
Administration: Subcutaneous injection, typically administered nightly.
Tesamorelin
Tesamorelin is an FDA-approved GHRH analog specifically indicated for reducing visceral abdominal fat. Originally developed for HIV-associated lipodystrophy, tesamorelin has become increasingly used off-label for body composition optimization in the anti-aging space.
How it works: Tesamorelin has the strongest clinical data specifically for visceral fat reduction — the deep belly fat surrounding your organs that is most closely linked to metabolic disease, cardiovascular risk, and insulin resistance. Studies show significant reductions in trunk fat with tesamorelin treatment.
Key benefits:
- Strongest clinical evidence for visceral fat reduction
- Improved metabolic health markers
- Reduced cardiovascular risk factors
- FDA-approved with robust safety data
Administration: Daily subcutaneous injection.
The CJC-1295 + Ipamorelin Combination
This is our most commonly prescribed peptide protocol. By combining CJC-1295 (working through GHRH receptors) with ipamorelin (working through ghrelin receptors), you get synergistic stimulation through two independent pathways simultaneously. The result is a more robust and sustained growth hormone release than either peptide alone. Read more about the benefits of sermorelin and ipamorelin combination therapy.
Benefits of the combination include improved sleep quality, accelerated fat loss, increased lean muscle mass, enhanced recovery, better skin quality, and improved cognitive function.
Benefits of Peptide Therapy
When the right peptides are matched to your biology and goals, the improvements span sleep, body composition, recovery, and overall vitality.
Deeper Sleep
Growth hormone peptides enhance deep wave sleep — often the first improvement patients notice within 2-4 weeks.
Improved Body Composition
Reduced body fat — especially visceral abdominal fat — and increased lean muscle mass through natural GH optimization.
Faster Recovery
Accelerated tissue repair, reduced inflammation, and shorter recovery times between workouts and after injuries.
Injury Healing
BPC-157 and TB-500 promote angiogenesis, growth factor expression, and cell migration to repair damaged tissue.
Skin & Collagen
Enhanced skin elasticity and collagen production for a more youthful appearance through optimized growth hormone.
Gut Health
BPC-157 repairs intestinal lining and reduces GI inflammation — beneficial for IBS, IBD, leaky gut, and NSAID damage.
Tissue Repair and Recovery Peptides
BPC-157 (Body Protection Compound)
BPC-157 is a synthetic peptide derived from a protein naturally found in human gastric juice. It has become one of the most popular peptides in sports medicine and regenerative health due to its remarkable tissue-healing properties.
Mechanism of action:
- Promotes angiogenesis (formation of new blood vessels to injured areas)
- Stimulates growth factor expression in damaged tissues
- Reduces inflammation through multiple pathways
- Protects and repairs the gastrointestinal lining
- Has demonstrated neuroprotective properties in preclinical studies
Administration: Subcutaneous injection near the injury site, or oral capsules for GI-specific benefits. Typical treatment duration is 4-8 weeks for acute injuries.
TB-500 (Thymosin Beta-4)
TB-500 is a synthetic version of thymosin beta-4, a naturally occurring peptide involved in tissue repair, cell migration, and anti-inflammatory responses. It works systemically — unlike BPC-157 which works best near the injection site, TB-500 circulates throughout the body to find and repair damaged tissue.
TB-500 and BPC-157 are frequently stacked together for enhanced healing — BPC-157 for localized repair at the injury site and TB-500 for systemic anti-inflammatory and repair support.
Peptide Therapy Comparison
Each peptide has a distinct mechanism and use case. We select the right one — or combination — based on your goals.
| Peptide | Primary Purpose | Mechanism | Administration | Best For |
|---|---|---|---|---|
| Sermorelin | GH optimization | GHRH receptor agonist | Nightly injection | Sleep, anti-aging, body composition |
| CJC-1295 | Sustained GH elevation | Long-acting GHRH analog | 2-3x weekly injection | Sustained GH support, lean mass |
| Ipamorelin | Selective GH release | Ghrelin receptor agonist | Nightly injection | Clean GH boost, fewer side effects |
| Tesamorelin | Visceral fat reduction | GHRH analog (FDA-approved) | Daily injection | Belly fat, metabolic health |
| BPC-157 | Tissue repair | Angiogenesis, growth factors | Injection or oral | Injuries, gut healing, recovery |
| TB-500 | Systemic repair | Cell migration, anti-inflammatory | 2x weekly injection | Chronic injuries, inflammation, flexibility |
Our Process at Rewind Anti-Aging
From consultation to optimization — every step is lab-guided and personalized to your biology.
Consultation
Discuss your goals, health history, injuries, and what you're trying to achieve.
Blood Work
Baseline IGF-1, comprehensive metabolic panel, and relevant markers to assess your current growth hormone status and overall health.
Protocol Design
Based on your labs and goals, we select the right peptide(s), dosing schedule, and treatment duration.
Injection Training
We teach you how to self-administer subcutaneous injections at home. It's simple, nearly painless, and takes seconds.
Monitoring
Follow-up labs at 8-12 weeks to assess response. We adjust dosing and protocol based on your results and how you feel.
Side Effects and Safety
Therapeutic peptides have a generally favorable safety profile when prescribed appropriately and monitored by a medical professional.
Common side effects (typically mild):
- Injection site redness, itching, or mild irritation
- Temporary water retention during initial weeks
- Tingling or numbness in extremities (usually resolves with dose adjustment)
- Increased hunger (particularly with ghrelin-based peptides like ipamorelin)
- Mild headache during initial treatment
Contraindications:
- Active cancer or history of cancer (growth hormone peptides can promote cell growth)
- Pregnancy or breastfeeding
- Uncontrolled diabetes
- Active infection (for BPC-157/TB-500 — while they promote healing, treatment should begin after acute infection resolves)
We require baseline blood work (including IGF-1) before prescribing any peptide and monitor your progress with follow-up labs at 8-12 weeks.
Who Benefits from Peptide Therapy?
- Adults Experiencing Age-Related Decline
Declining energy, poor sleep, increased body fat, loss of muscle tone, slower recovery. Growth hormone peptides address these directly.
- Athletes & Fitness Enthusiasts
Accelerated recovery, improved body composition, injury prevention and healing.
- Patients with Injuries or Chronic Pain
BPC-157 and TB-500 for tendon/ligament injuries, joint issues, and post-surgical recovery.
- People with GI Issues
BPC-157 for gut healing, intestinal lining repair, and reducing GI inflammation.
- Patients on Hormone Therapy
Peptides complement HRT by adding growth hormone optimization to the protocol for synergistic results.
- Anyone Focused on Longevity
Maintaining optimal growth hormone levels is increasingly recognized as a key component of healthy aging.
What BPC-157 and TB-500 Treat
BPC-157 is used for:
- Musculoskeletal injuries — tendon, ligament, and muscle repair. Accelerates healing of strains, sprains, and tears
- Joint health — supports cartilage repair and reduces joint inflammation
- Gut healing — repairs intestinal lining, beneficial for IBS, IBD, leaky gut, and NSAID-induced gut damage
- Post-surgical recovery — promotes tissue repair and reduces recovery time
- Organ protection — studies show protective effects on liver, heart, and brain tissue
TB-500 key benefits:
- Accelerated wound healing and tissue repair
- Reduced inflammation and scar tissue formation
- Improved flexibility and reduced stiffness
- Promotion of new blood vessel growth in damaged areas
- Hair regrowth support (thymosin beta-4 has demonstrated effects on hair follicle stem cells)
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Six Peptides Available
Sermorelin, CJC-1295, ipamorelin, tesamorelin, BPC-157, and TB-500. We select based on your needs, not limited inventory.
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Integrated Approach
Peptides work best as part of a comprehensive strategy that includes hormone therapy, nutrition, and lifestyle. We design protocols that work together.
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Lab-Guided Prescribing
Every protocol starts with bloodwork and includes follow-up monitoring. We don't prescribe blindly.
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Pharmaceutical-Grade Sourcing
All peptides sourced from licensed compounding pharmacies that meet USP standards.
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Education First
We explain what each peptide does, why we're recommending it, and what to expect. You understand your treatment.
Peptide Therapy Insights from Our Blog
What Is Peptide Therapy?
Everything you need to know about peptide therapy and its clinical uses.
Sermorelin and Ipamorelin: Combination Therapy
How two popular peptides work together for growth hormone optimization.
Best Peptides for Weight Loss
Which peptides support fat loss and metabolic health.
Best Peptides to Increase Testosterone
How peptide therapy supports healthy testosterone levels.
Peptide Therapy Stacks: Combining Peptides for Maximum Results
The most effective peptide combinations for fat loss, recovery, and anti-aging.
Frequently Asked Questions About Peptide Therapy
What are peptides?
Peptides are short chains of amino acids — the building blocks of proteins. Your body naturally produces thousands of peptides that act as signaling molecules, telling cells what to do. Therapeutic peptides are synthetic versions of these natural compounds, designed to stimulate specific biological processes like growth hormone production, tissue repair, or immune modulation.
Are peptides the same as steroids or HGH?
No. Peptides like sermorelin and ipamorelin are growth hormone secretagogues — they stimulate your pituitary gland to produce its own growth hormone naturally. They do not introduce synthetic growth hormone into your body. This means your body's natural feedback mechanisms remain intact, producing a more physiological and safer response than exogenous HGH.
Are peptides safe?
When prescribed by a medical professional and used at appropriate doses, therapeutic peptides have a strong safety profile. Side effects are generally mild — injection site reactions, temporary water retention, or tingling. Serious adverse effects are rare. We monitor your progress and lab work to ensure safety throughout your treatment.
How are peptides administered?
Most peptides are administered via subcutaneous injection (a small needle into the fat layer just beneath the skin, similar to an insulin injection). BPC-157 can also be taken orally in capsule form for GI-specific benefits. We teach you the injection technique — it's simple and nearly painless.
How long does it take to see results from peptide therapy?
It depends on the peptide and your goals. Growth hormone secretagogues (sermorelin, CJC-1295, ipamorelin) typically show initial improvements in sleep quality and energy within 2-4 weeks, with body composition changes becoming visible at 2-3 months. BPC-157 for injury healing can show improvement within 1-2 weeks. Full optimization usually takes 3-6 months.
Can I combine peptides with hormone therapy?
Yes, and many patients do. Peptides and HRT are complementary — hormone therapy optimizes your baseline hormone levels while peptides enhance growth hormone production, tissue repair, and recovery. The combination often produces synergistic results greater than either treatment alone.
Do I need blood work before starting peptides?
Yes. We run baseline labs including IGF-1 (the primary marker for growth hormone status), comprehensive metabolic panel, and other relevant markers. This establishes your starting point and helps us select the right peptide protocol. Follow-up labs at 8-12 weeks confirm the treatment is working.
How long do I need to take peptides?
Treatment duration varies. Growth hormone peptides are typically used in cycles of 3-6 months, sometimes with breaks between cycles. BPC-157 for acute injury healing may only be needed for 4-8 weeks. Ongoing maintenance protocols are common for patients using peptides as part of a long-term anti-aging strategy. We design your protocol based on your goals.
What is the difference between sermorelin, CJC-1295, and ipamorelin?
All three stimulate growth hormone release but through slightly different mechanisms. Sermorelin mimics GHRH (the natural hormone that signals GH release). CJC-1295 is a modified GHRH analog with a longer half-life. Ipamorelin works through ghrelin receptors. They're often combined — particularly CJC-1295 + ipamorelin — for synergistic effects.
Will peptides show up on a drug test?
Peptides are not standard panel substances in workplace drug testing. However, they are banned by most professional sports organizations (WADA, NCAA, etc.). If you're a competitive athlete subject to anti-doping testing, discuss this with your provider before starting any peptide protocol.
Explore What Peptides Can Do for You
Schedule a consultation to discuss your goals and get baseline labs. We'll design a peptide protocol tailored to your biology.
⚕ Medical Disclaimer
The information on this page is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. All treatments at Rewind Anti-Aging of Miami are performed under the supervision of licensed medical professionals. Individual results may vary. Consult your physician before beginning any new treatment protocol.
Meet our clinical team →Areas We Serve in Miami & South Florida
Our Wynwood clinic at 24 NW 29th Street serves patients across the Miami metro in person and the entire state of Florida via telehealth.