Tadalafil (Cialis) Treatment

Our tadalafil uses the same active ingredient as Cialis — tadalafil, a PDE5 inhibitor. The difference is our formulation. We compound tadalafil into mini-troches (small sublingual tablets) that can be combined with complementary active ingredients like oxytocin, testosterone, and sermorelin in a single dose. This multi-ingredient approach addresses the vascular, hormonal, and emotional dimensions of sexual function simultaneously — something a standard Cialis tablet cannot do.

Tadalafil has a half-life of approximately 17.5 hours, meaning its effects can last up to 36 hours after a single dose. This is why tadalafil is often called 'the weekend pill' — a dose taken on Friday evening can still be effective on Sunday morning. This long duration allows for significantly more spontaneity compared to sildenafil's 4-6 hour window. Tadalafil does not cause a continuous erection; sexual stimulation is still required.

Both approaches are valid, and the right choice depends on your lifestyle. On-demand tadalafil (10-20 mg taken before anticipated sexual activity) is ideal if you are sexually active a few times per month and prefer taking medication only when needed. Daily tadalafil (2.5-5 mg taken every day regardless of activity) is better if you prefer continuous readiness without planning around a pill, or if you also have BPH symptoms. Daily dosing maintains a steady level in your system. Your provider will recommend the best approach for your situation.

The most common side effects are headache, facial flushing, nasal congestion, indigestion, and back pain or muscle aches. Back and muscle pain are more commonly associated with tadalafil than sildenafil and typically occur 12 to 24 hours after dosing, resolving within 48 hours. Side effects are generally mild and tend to diminish with continued use. Tadalafil is contraindicated with nitrate medications due to the risk of severe hypotension.

Both are PDE5 inhibitors that work through the same mechanism — blocking the enzyme that degrades cGMP to enhance penile blood flow during arousal. The key differences are duration and flexibility. Sildenafil works within 30-60 minutes and lasts 4-6 hours — best for planned use. Tadalafil works within 30 minutes to 2 hours and lasts up to 36 hours, providing a much longer window. Tadalafil is also unaffected by food and is available as a daily low-dose option. Many men prefer tadalafil for its spontaneity.

Yes. Tadalafil is a prescription medication that requires a medical evaluation. At Rewind Anti-Aging, our providers assess your symptoms, cardiovascular health, current medications, and underlying causes of ED before prescribing. We also evaluate hormonal factors like testosterone that may be contributing to your symptoms. All custom compounds are prepared by licensed compounding pharmacies meeting USP quality standards.